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MICROCHIPS & VACCINES - CASE STUDY:

Fibrosarcoma with Typical Features of Postinjection Sarcoma at Site of Microchip Implant in a Dog: Histologic and Immunohistochemical Study.
M. Vascellari, E. Melchiotti and F. Mutinelli.
Istituto Zooprofilattico Sperimentale delle Venezie, Histopathology Department, Viale dell'Universita 10, 35020 Legnaro (PD), Italy.
Vet Pathol 43:545-548 (2006).
This paper was published in Veterinary Pathology regarding Leon’s case. The Abstract (free) is available online. Click here.

MICROCHIPS - CASE STUDIES:
Electronic Identification, Radio Frequency Identification (RFID), National Animal Identification System (NAIS), Subcutaneous Microchip for Human Identification (SMHId)

Liposarcoma at the site of an implanted microchip in a dog.
Vascellari M, Mutinelli F, Cossettini R, Altinier E.
Istituto Zooprofilattico Sperimentale delle Venezie, Histopathology Department, Viale dell'Universita 10, 35020 Legnaro (PD), Italy.
Vet J. 2004 Sep;168(2):188-90.
www.ncbi.nlm.nih.gov

The Summary of: Liposarcoma at the site of an implanted microchip in a dog (Liposarcoma In Sede Di Applicazione Del Microchip In Un Cane : A.P.I.V. - Associazione Italiana Patologi Veterinari: ATTI del XXI Convegno Nazionale) is available at:
www.aipvet.it

Microchip-Associated Tumour In A C57/BL Mouse.
GTP Meeting 2000: Case No 15.
www.eurotoxpath.org

Subcutaneous microchip-associated tumours in B6C3F1 mice: a retrospective study to attempt to determine their histogenesis.
Le Calvez S, Perron-Lepage MF, Burnett R.
Ecole Nationale Veterinaire, Unite d'Anatomie Pathologique, 44307 Nantes, France.
Exp Toxicol Pathol. 2006 Mar;57(4):255-65. Epub 2006 Jan 19.
www.ncbi.nlm.nih.gov

Subcutaneous soft tissue tumours at the site of implanted microchips in mice.
Tillmann T, Kamino K, Dasenbrock C, Ernst H, Kohler M, Morawietz G, Campo E, Cardesa A, Tomatis L, Mohr U.
Institute of Experimental Pathology, Hannover Medical School, Germany.
Exp Toxicol Pathol. 1997 Aug;49(3-4):197-200.
www.ncbi.nlm.nih.gov

Transponder-induced sarcoma in the heterozygous p53+/- mouse.
Blanchard KT, Barthel C, French JE, Holden HE, Moretz R, Pack FD, Tennant RW, Stoll RE.
Department of Toxicology and Safety Assessment, Boehringer Ingelheim Pharmaceuticals, Ridgefield, Connecticut 06877, USA.
Toxicol Pathol. 1999 Sep-Oct;27(5):519-27.
www.ncbi.nlm.nih.gov

Tumors in long-term rat studies associated with microchip animal identification devices.
Elcock LE, Stuart BP, Wahle BS, Hoss HE, Crabb K, Millard DM, Mueller RE, Hastings TF, Lake SG.
Bayer Corporation, Toxicology Department, Stilwell, Kansas 66085, USA.
Exp Toxicol Pathol. 2001 Feb;52(6):483-91.
www.ncbi.nlm.nih.gov

VACCINES - CASE STUDIES:

Clinical use of serum parvovirus and distemper virus antibody titers for determining revaccination strategies in healthy dogs.
Lisa Twark, DVM; W. Jean Dodds, DVM.
Hemopet and Antech Diagnostics, 17672A Cowan Ave, Irvine, CA 92614.
Journal of the American Veterinary Medical Association.
October 1, 2000, Vol. 217, No. 7, Pages 1021-1024.
avmajournals.avma.org

Do postvaccinal sarcomas occur in Australian cats?
G Burton and KV Mason.
Animal Skin and Allergy Clinic, 3331 Pacific Highway, Springwood, Queensland 4127.
Aust Vet J 1997; 75:102-106.
www.ava.com.au

Effects of vaccines on the canine immune system.
T R Phillips, J L Jensen, M J Rubino, W C Yang, and R D Schultz.
Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin-Madison 53706.
Can J Vet Res. 1989 April; 53(2): 154–160.
www.pubmedcentral.nih.gov

Epidemiologic evidence for a causal relation between vaccination and fibrosarcoma tumorigenesis in cats.
Kass PH, Barnes WG Jr, Spangler WL, Chomel BB, Culbertson MR.
Department of Epidemiology and Preventive Medicine, School of Veterinary Medicine, University of California, Davis 95616-8735.
J Am Vet Med Assoc. 1993 Aug 1;203(3):396-405.
www.ncbi.nlm.nih.gov

Feline Vaccine-associated Fibrosarcoma: Morphologic Distinctions.
S. S. Couto, S. M. Griffey, P. C. Duarte and B. R. Madewell.
Veterinary Medical Teaching Hospital, University of California, School of Veterinary Medicine, Davis, CA (SSC), and Department of Pathology, Microbiology and Immunology (SMG), Medicine and Epidemiology (PCD), and Surgical and Radiological Sciences (BRM), University of California, School of Veterinary Medicine, Davis, CA.
Vet Pathol 39:33-41 (2002).
www.vetpathology.org

Fibrosarcomas at presumed sites of injection in dogs: characteristics and comparison with non-vaccination site fibrosarcomas and feline post-vaccinal fibrosarcomas.
Vascellari M, Melchiotti E, Bozza MA, Mutinelli F.
Istituto Zooprofilattico Sperimentale delle Venezie, Histopathology Department, Viale dell'Universita 10, 35020 Legnaro (PD), Italy.
J Vet Med A Physiol Pathol Clin Med. 2003 Aug;50(6):286-91.
www.ncbi.nlm.nih.gov

Histology and Immunohistochemistry of Seven Ferret Vaccination-site Fibrosarcomas.
J. S. Munday, N. L. Stedman and L. J. Richey.
Athens Diagnostic Laboratory and Department of Veterinary Pathology, College of Veterinary Medicine, University of Georgia, Athens, GA.
Vet Pathol 40:288-293 (2003).
www.vetpathology.org

Prognosis for presumed feline vaccine-associated sarcoma after excision: 61 cases (1986–1996).
Elizabeth Hershey, DVM; Karin U. Sorenmo, CMV, DACVIM; Mattie J. Hendrick, VMD, DACVP; Frances S. Shofer, PhD; David M. Vail, DVM, DACVIM.
Journal of the American Veterinary Medical Association.
January 1, 2000, Vol. 216, No. 1, Pages 58-61.
avmajournals.avma.org

Pulmonary and mediastinal metastases of vaccination-site sarcoma in a cat.
D. G. Rudmann, W. G. Van Alstine, F. Doddy, G. E. Sandusky, T. Barkdull and E. B. Janovitz.
Genentech, Inc., South San Francisco, CA 94080, USA.
Veterinary Pathology, Vol 33, Issue 4 466-469.
www.vetpathology.org

The potential role of inflammation in the development of postvaccinal sarcomas in cats.
Macy DW, Hendrick MJ.
School of Veterinary Medicine, Colorado State College, Fort Collins 80523, USA.
Vet Clin North Am Small Anim Pract. 1996 Jan;26(1):103-9.
www.ncbi.nlm.nih.gov

Vaccine-associated Rhabdomyosarcoma with Spinal Epidural Invasion and Pulmonary Metastasis in a Cat.
H.-W Chang, S.-Y Ho, H.-F Lo, Y.-C Tu, C.-R Jeng, C.-H Liu, F.-I Wang and V. F. Pang.
Vet Pathol 43:55-58 (2006).
www.vetpathology.org

Vaccine Site-Associated Sarcoma and Malignant Lymphoma in Cats: A Report of Six Cases (1997–2002).
Bruce R. Madewell, VMD, Diplomate ACVIM (Oncology Internal Medicine), Tracy L. Gieger, DVM, Diplomate ACVIM (Internal Medicine), Patricia A. Pesavento, DVM, PhD and Michael S. Kent, DVM, Diplomate ACVIM (Oncology).
From the Veterinary Medical Teaching Hospital, School of Veterinary Medicine, University of California, Davis, California 95616.
Journal of the American Animal Hospital Association 40:47-50 (2004).
www.jaaha.org


VACCINES - DISCUSSIONS, PRESENTATIONS & REPORTS:

Adverse Vaccine Reactions.
W. Jean Dodds, DVM.
www.noble-leon.com
This article has been reproduced on this website with the permission of Dr. Dodds.

Avoiding Vaccine Reactions in Dogs and Cats.
Craig E. Greene.
28th World Congress of the World Small Animal Veterinary Association: October 24 – 27, 2003: Bangkok, Tailand.
www.vin.com

Feline Postvaccinal Sarcoma: A 2004 Update.
Histovet Surgical Pathology.
www.histovet.com

Feline Vaccine-Associated Sarcomas.
Barbara E. Kitchell, DVM, PhD, DACVIM.
30 th World Congress of the World Small Animal Veterinary Association: May 11 – 14, 2005: Mexico City, Mexico.
www.vin.com/proceedings

Infectious Disease Prevention Change is in the Wind.
Richard B. Ford, DVM, MS, DACVIM, DACVPM (Hon).
30 th World Congress of the World Small Animal Veterinary Association: May 11 – 14, 2005: Mexico City, Mexico.
www.vin.com/proceedings

Injection Site and Vaccine Associated Sarcomas: New Advances for a New Millennium.
Gregory K. Ogilvie, DVM, DACVIM (Internal Medicine, Oncology).
29 th World Congress of the World Small Animal Veterinary Association: October 6 – 9, 2004: Rhodes, Greece.
www.vin.com

Update on Feline Fibrosarcoma.
Patrick Devauchelle, DVM
27 WSAVA CONGRESS.
www.vin.com

Vaccination Protocols for Dogs Predisposed to Vaccine Reactions.
W. Jean Dodds, DVM
Journal of the American Animal Hospital Association.
May/June 2001, Vol. 37, Pages 211-214.
This article has been reproduced on this website with the permission of Dr. Dodds.
www.noble-leon.com

Vaccine-Associated Feline Sarcoma Task Force: Roundtable Discussion - The current understanding and management of vaccine-associated sarcomas in cats.
JAVMA: June 1, 2005; Vol. 226, No. 11.
www.avma.org

Vaccine-associated feline sarcomas.
Wallace B. Morrison, DVM, MS, DACVIM; Robin M. Starr, DVM, MEd; and the Vaccine-Associated Feline Sarcoma Task Force.
Report of the Vaccine-Associated Feline Sarcoma Task Force from the Journal of the AVMA, Vol 218, No. 5, March 1, 2001, pp. 697-702.
www.avma.org

Vaccine-Associated Sarcomas in the Cat.
Glenna Mauldin.
World Small Animal Veterinary Association World Congress: 2001: Vancouver.
www.vin.com

MISCELLANEOUS:

EMEA Public Bulletin 2003 On Veterinary Pharmacovigilance.
The European Agency for the Evaluation of Medicinal Products; Veterinary Medicines and Inspections.
www.emea.europa.eu

EMEA Public Bulletin 2005 On Veterinary Pharmacovigilance.
European Medicines Agency; Veterinary Medicines and Inspections.
www.emea.europa.eu

Debilitating ossifying fibromas of a white-tailed deer associated with ear tagging.
DE Roscoe, LR Veikley, M Mills Jr, and L Hinds 3rd.
Journal of Wildlife Diseases, 11(1), 1975, pp. 62-65.
www.jwildlifedis.org

Liposarcoma associated with a glass foreign body in a dog.
McCarthy PE, Hedlund CS, Veazy RS, Prescott-Mathews J, Cho DY.
Department of Veterinary Clinical Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge 70803, USA.
J Am Vet Med Assoc. 1996 Aug 1;209(3):612-4.
www.ncbi.nlm.nih.gov

Tumorigenicity of sarcoma cells is enhanced by the local environment of implanted foreign body.
Vasiliev JuM, Moizhess TG.
Int J Cancer. 1982 Oct 15;30(4):525-9.
www.ncbi.nlm.nih.gov

Last Updated: February 2007